NFL 2023: Week 2 Betting

Week 2 is already here. Check out each best bet (courtesy of BetMGM) below.

First & Jenn’s Game of the Week:

Minnesota Vikings @ Philadelphia Eagles

When: Thursday, September 14, 2023 @ 8:15 PM ET

Notes: Both teams meet again in primetime. The Eagles look to have another flawless record early in the season, but the Vikings are looking for revenge.

All-Time History: MIN leads series, 15-11

Prediction: Eagles

Best Bet: Justin Jefferson Anytime TD (-125)

First & Jenn’s Game to Skip:

Indianapolis Colts @ Houston Texans

When: Sunday, September 17, 2023 @ 1:00 PM ET

Notes: Both rookie quarterbacks look to break records this week as they continue to develop with their teams.

All-Time History: IND leads series, 31-10-1

Prediction: Colts

Best Bet: A. Richardson O 198.5 Passing Yards (-115)

Green Bay Packers @ Atlanta Falcons

When: Sunday, September 17, 2023 @ 1:00 PM ET

Notes: Teams with young quarterbacks look to take the win this weekend. Both teams are basically on equal footing heading into this matchup.

All-Time History: GB leads series, 17-14

Prediction: Packers

Best Bet: J. Bates II O 5.5 Tackles+Assists (+105)

Las Vegas Raiders @ Buffalo Bills

When: Sunday, September 17, 2023 @ 1:00 PM ET

Notes: Garoppolo had a good Week 1, Allen not so much. The Raiders are looking for their second win to immediately turn things around from last season, but the Bills window of opportunity is closing.

All-Time History: LV leads series, 21-19

Prediction: Bills

Best Bet: Total O 47.5 (+100)

Baltimore Ravens @ Cincinnati Bengals

When: Sunday, September 17, 2023 @ 1:00 PM ET

Notes: There are quite a few storylines to follow this week. One quarterback had a great Week 1, the other did not. Jackson and the Ravens look to begin 2-0 for the first time since 2020, but the Bengals look for an answer to their Week 1 loss.

All-Time History: BAL leads series, 28-26

Prediction: Bengals

Best Bet: Total O 48 (+105)

Seattle Seahawks @ Detroit Lions

When: Sunday, September 17, 2023 @ 1:00 PM ET

Notes: Both quarterbacks had an average Week 1 performance. It will be interesting to see how they answer this week.

All-Time History: SEA leads series, 11-5

Prediction: Lions

Best Bet: Total O 44.5 (-150)

Kansas City Chiefs @ Jacksonville Jaguars

When: Sunday, September 17, 2023 @ 1:00 PM ET

Notes: I’m very interested in this matchup because with Kelce gone, the Jaguars kind of have a shot to dominate much, if not all, of this game.

All-Time History: KC leads series, 8-6

Prediction: Jaguars

Best Bet: Jaguars ML (+150)

Chicago Bears @ Tampa Bay Buccaneers

When: Sunday, September 17, 2023 @ 1:00 PM ET

Notes: The Bears had a troubling start to the season, but I think they find their footing against Baker Mayfield and the Buccaneers. The Bears wipe the board in offensive and defensive stats against the Bucs this season.

All-Time History: CHI leads series, 40-21

Prediction: Bears

Best Bet: J. Fields O 175.5 Passing Yards (-115)

Los Angeles Chargers @ Tennessee Titans

When: Sunday, September 17, 2023 @ 1:00 PM ET

Notes: I haven’t been too confident in the Titans, so I think the Chargers bounce back this week.

All-Time History: LAC leads series, 28-15-1

Prediction: Chargers

Best Bet: Justin Herbert O 1.5 Passing TDs (-155)

New York Giants @ Arizona Cardinals

When: Sunday, September 17, 2023 @ 4:05 PM ET

Notes: Coming off of a terrible Week 1, I think the Giants bounce back against the Cardinals having experience against head coach Johnathan Gannon.

All-Time History: NYG leads series, 80-46-2

Prediction: Giants

Best Bet: D. Jones O 1.5 Passing TDs (+140)

San Francisco 49ers @ Los Angeles Rams

When: Sunday, September 17, 2023 @ 4:05 PM ET

Notes: The 49ers had a fierce week last week, but now they face Aaron Donald and the Rams defense. I’m very interested in seeing how the 49ers work in real adversity.

All-Time History: SF leads series, 76-67-3

Prediction: 49ers

Best Bet: B. Purdy O 1.5 Pass TDs (-105)

New York Jets @ Dallas Cowboys

When: Sunday, September 17, 2023 @ 4:25 PM ET

Notes: With Aaron Rodgers down, I think the Cowboys might have their way against the Jets – but the Jets are also a lot younger and faster.

All-Time History: DAL lead series, 7-5

Prediction: Cowboys

Best Bet: Tot O 39.5 (+100)

Washington Commanders @ Denver Broncos

When: Sunday, September 17, 2023 @ 4:25 PM ET

Notes: Sam Howell had an impressive Week 1 versus the Cardinals and now visit the Broncos who look to get their first win of the season with a pretty good defense. 

All-Time History: DEN lead series, 8-6

Prediction: Broncos

Best Bet: Broncos ML (-185)

Miami Dolphins @ New England Patriots

When: Sunday, September 17, 2023 @ 8:20 PM ET

Radio: Westwood One: Ryan Radtke, Mike Golic

Notes: The Dolphins come off of a fiery Week 1 totaling the most yards of any offense since 2019 with 536 yards. The Patriots look to bounce back and scheme against this intense Miami offense.

All-Time History: MIA leads series, 59-53

Prediction: Dolphins

Best Bet: Dolphins ML (-160)

New Orleans Saints @ Carolina Panthers

When: Monday, September 18, 2023 @ 7:15 PM ET

Notes: The Saints are coming off of a close win last week to start strong, but the Panthers have the upperhand with home field and playing a Monday Night Football game for the first time since December 2018 against the Saints.

All-Time History: Series tied, 28-28

Prediction: Saints

Best Bet: Total O 40 (-110)

Cleveland Browns @ Pittsburgh Steelers

When: Monday, September 18, 2023 @ 8:15 PM ET

Notes: The Browns have the opportunity to go 2-0 on the season for the first time since 1993, but the Steelers look to bounce back from a tough loss on the road against the 49ers.

All-Time History: PIT leads series, 78-61-1

Prediction: Browns

Best Bet: Browns ML (-140)

Subscribe to First & Jenn for NFL news, content and betting all season long!